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Copyright 2007 ©
Cancer Control using Populationbased Registries and Biobanks. |
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Background, Biobank-based studies |
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Longitudinal studies nested in biobanks enable more reliable and
efficient study designs, both for design and evaluation of cancer
treatment and cancer prevention as well as for exploring and
evaluating etiologic hypotheses.
However, several prerequisites apply:
- There must exist very large scale biobanks that should
already have several decades of follow-up.
- It must be possible to link biobanks with quality-assured
population-based cancer registries to enable
population-representative studies with minimal case
ascertainment bias.
- Important problems regarding overview, accessibility,
quality control, phenotypic characterisation, efficiency and
avoiding risks for violation of personal integrity must be
addressed.
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